Frequently asked questions

PI is a chronic condition in which the body is missing part of the immune system or it doesn't function properly. PI comes in many different forms and certain types occur when antibodies that help fight infection are missing from the blood. Without these antibodies, people with PI have a higher chance of getting infections. It can be difficult to diagnose PI as the signs and symptoms vary from person to person depending on the type.

PI is typically treated by replacing the missing antibodies in the immune system with a subcutaneous immunoglobulin (SCIg), such as cutaquig.

Cutaquig is a treatment for adult and pediatric patients aged 2 years and older with PI. Cutaquig is a liquid medicine for infusion that contains immunoglobulin G (IgG), which is an antibody that helps fight infection. It is infused subcutaneously (under the skin) and is known as an SCIg therapy. Cutaquig is administered with an infusion pump and subcutaneous needles and can be infused at home—by you or your caregiver—after proper training or by a specialized healthcare provider.

• Cutaquig can make vaccines (like measles/mumps/rubella or chickenpox vaccines) not work as well for you. Before you get any vaccines, tell your healthcare provider that you take cutaquig
• Tell your healthcare provider if you are pregnant, or plan to become pregnant, or if you are nursing

Cutaquig is given under the skin (subcutaneous) with an infusion pump and subcutaneous needles. Most of the time, infusions under the skin are given at home by self-infusion or by a caregiver. Because cutaquig can be self-administered, you and your healthcare provider or caregiver can discuss the dosing schedule that fits best with your lifestyle.

Flexible dosing options (either every-other-week, weekly, or more frequent dosing [2-7 times a week]) allow you to infuse cutaquig at times and on days that best fit your schedule. Only use cutaquig by yourself after you have been instructed on use by a healthcare provider.

Watch this instructional video on self-administration of cutaquig.

In a clinical study, 75 adult and pediatric patients treated with cutaquig experienced no serious bacterial infections during the 52-week efficacy study period.*

^*Prospective, open-label, noncontrolled, single-arm, mutlicenter, clinical study to evaluate weekly subcutaneous infusions of cutaquig in a total of 75 patients with PI (37 adult patients and 38 pediatric patients <17 years of age).

The most common side effects of cutaquig are:

• Infusion-site reactions (including but not limited to mild or moderate pain, redness, swelling, itching)
• Headache
• Elevated body temperature

It is important to keep an infusion journal to record details of each cutaquig infusion, so that your healthcare provider can monitor your progress. Be sure to fill out every section and keep an accurate record of each time you administer cutaquig. Please remember to bring your journal to any appointments with your healthcare provider. During your first few infusions, it is recommended that you ask your infusion nurse or trainer to help you complete your journal.

Download the infusion journal to track when you administer cutaquig. Click here to download the Full Prescribing Information.

Download Ig Companion to track, manage, and export your infusion information to help you get the most out of your doctor visits.

To administer cutaquig, you’ll need cutaquig vials (per your healthcare provider’s prescription), an infusion pump and compatible syringes, subcutaneous needles, special tubing provided by your specialty pharmacy, a sharps container, and an infusion journal.

Watch this instructional video on self-administration of cutaquig.

Cutaquig may be refrigerated at 36^oF to 46^oF (2^oC to 8^oC) for up to 36 months from the date of manufacture. Within its 36-month shelf life, cutaquig may be removed from the refrigerator and stored at room temperature up to
77^oF (25^oC) for up to 9 months without being refrigerated again, and must be discarded if not used after this. Do not freeze cutaquig, and do not use frozen product. Keep the vial in the carton to protect it from light.